Alabama vs. S. Carolina Football Prediction & Odds - Oct. 25

The No. 4 Alabama Crimson Tide (6-1) hit the road for an SEC battle against the South Carolina Gamecocks (3-4) on Saturday, October 25, 2025 at Williams-Brice Stadium.

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Alabama vs. South Carolina Matchup Info

  • Game date: Saturday, October 25, 2025
  • Game time: 3:30 p.m. ET
  • Location: Columbia, South Carolina
  • Venue: Williams-Brice Stadium
  • TV channel: ABC
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Alabama vs. South Carolina Odds and Prediction

  • Spread favorite: Crimson Tide (-11.5)
  • Moneyline: Crimson Tide (-455), Gamecocks (+351)
  • Total: 47.5 points
  • Pick ATS: Alabama (-11.5)
  • Pick OU: Under (47.5)
  • Prediction: Alabama 31, South Carolina 15

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Alabama vs. South Carolina Betting Records and Insights

  • Alabama has won five games against the spread this season, while failing to cover twice.
  • South Carolina has won three games against the spread this season, failing to cover four times.
  • The Crimson Tide have been favored by 11.5 points or more four times this season, and covered the spread in three of those contests.
  • So far this season, three of Alabama's seven games have gone over the point total.
  • So far this season, two South Carolina games have gone over the point total.

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