SEC opponents meet when the No. 11 LSU Tigers (4-1) and the South Carolina Gamecocks (3-2) square off on Saturday, October 11, 2025 at Tiger Stadium.
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LSU vs. South Carolina Matchup Info
- Game date: Saturday, October 11, 2025
- Game time: 7:45 p.m. ET
- Location: Baton Rouge, Louisiana
- Venue: Tiger Stadium
- TV channel: SEC Network
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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LSU vs. South Carolina Odds and Prediction
- Spread favorite: Tigers (-9)
- Moneyline: Tigers (-334), Gamecocks (+266)
- Total: 44.5 points
- Pick ATS: South Carolina (+9)
- Pick OU: Under (44.5)
- Prediction: LSU 23, South Carolina 15
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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LSU vs. South Carolina Betting Records and Insights
- LSU has covered twice in five games with a spread this season.
- South Carolina has compiled a 3-2-0 ATS record so far this season.
- The Tigers have not covered the spread when favored by 9 points or more this season (in two opportunities).
- The Gamecocks have won their only game this season when playing as at least 9-point underdogs.
- So far this season, just one LSU game has gone over the point total.
- This season, games featuring South Carolina have hit the over twice.